Methoxy-poly(ethylene glycol)5K-block-poly(D-lysine hydrochloride) is a linear amphiphilic block copolymer which has a poly(D-lysine hydrochloride) section and a non-reactive PEG5K section. It is a crystalline solid soluble in water. Upon derivatization of the poly(D-lysine hydrochloride) part, it can self-assemble into particles in aqueous solution with a hydrophobic poly(D-lysine) core and a hydrophilic PEG shell.
Product Description:
Poly-L-arginine hydrochloride is a positively charged synthetic polyamino acid having one HCl per arginine unit. It is a crystalline solid soluble in water. Applications for poly-L-arginine hydrochloride include the layer-by-layer deposition techniques and the complexation with nucleic acids for gene expression.
This particular poly-L-arginine hydrochloride has a trityl protected thiol on the C-terminal. The trityl group is easily cleavable using a TFA/Et3SiH (98:2 v/v) mixture.