
Polysarcosine is a polypeptoid made of the endogenous sarcosine amino acid (N-methylated glycine). It has PEG-like physicochemical properties such as water solubility and no reported cytotoxicity and immunogenicity. Lately, it is considered as a potential alternative to PEG in many bioapplications.
This particular polysarcosine has a DBCO function on the C-terminal and a non-reactive acetyl function on the N-terminal.